Skip to main content

Table 2 PM20D1 mQTL region genes and SNPs and their RNA expression correlations from GTEX and LIBD databases and our own cohort

From: Comprehensive analysis of PM20D1 QTL in Alzheimer’s disease

 rs1172198rs708727
 GTEX HipGTEX CBGTEX TNLIBD PFCLIBD HipFCXGTEX HipGTEX CBGTEX TNLIBD PFCLIBD HipFCX
NUCKS1n.s.n.s.3.30E−12n.s.n.s.n.s.n.s.1.80E−051.00E−11n.s.n.s.n.s.
RAB7L1n.s.4.00E−081.50E−12n.s.5.20E−06n.s.n.s.8.20E−077.80E−13n.s.4.40E−03n.s.
SLC41A1n.s.3.60E−065.00E−08n.s.n.s.n.s.n.s.2.00E−063.20E−10n.s.n.s.n.s.
PM20D11.40E−07n.s.1.90E−362.04E−71.34E−030.01852.40E−13n.s.1.60E−664.73E−143.83E−072.83E07
 rs823082rs823088
 GTEX HipGTEX CBGTEX TNLIBD PFCLIBD HipFCXGTEX HipGTEX CBGTEX TNLIBD PFCLIBD HipFCX
NUCKS1n.s.n.s.n.s.n.s.n.s.n.s.n.s.n.s.n.s.n.s.n.s.n.s.
RAB7L1n.s.n.s.4.30E−103.37E−046.71E−07n.s.n.s.n.s.n.s.8.25E−042.75E−05n.s.
SLC41A1n.s.n.s.7.40E−095.55E−03n.s.n.s.n.s.n.s.n.s.4.32E−04n.s.n.s.
PM20D13.20E−09n.s.1.40E−299.97E−060.025153.10E4n.s.n.s.3.20E−160.00279n.s.4.94E04
 rs1361754rs960603
 GTEX HipGTEX CBGTEX TNLIBD PFCLIBD HipFCXGTEX HipGTEX CBGTEX TNLIBD PFCLIBD HipFCX
NUCKS1n.s.n.s.n.s.n.s.n.s.n.s.n.s.n.s.7.60E−06n.s.n.s.n.s.
RAB7L1n.s.n.s.4.30E−102.61E−041.12E−06n.s.n.s.n.s.4.60E−06n.s.1.53E−03n.s.
SLC41A1n.s.n.s.7.40E−09n.s.n.s.0.0477n.s.n.s.n.s.n.s.n.s.n.s.
PM20D13.20E−09n.s.1.40E−292.18E−050.028874.85E06n.s.n.s.3.00E−296.25E−064.80E−050.0367
  1. Values in GTEX and LIBD columns represent gene expression and SNP correlation FDR-corrected p values from GTEX [12] (https://www.gtexportal.org) and LIBD (http://eqtl.brainseq.org) [13] datasets. GTEX, hippocampus (Hip) n = 111, cerebellum (CB) n = 154, tibial nerve (TN) n = 361; LIBD, dorsolateral prefrontal cortex (PFC) n = 412, hippocampus (Hip) n = 394. In italics, correlation p values obtained from our cohort of frontal cortex samples (FCX) n = 39. n.s. not significant