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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Comprehensive analysis of PM20D1 QTL in Alzheimer’s disease

Fig. 4

Functional validation of PM20D1 QTL genes in vitro. a PM20D1 QTL gene expression in SH-SY5Y cells after Aβ treatment. b PM20D1 QTL gene expression in SH-SY5Y cells after H2O2 treatment. c Cell viability of PM20D1 and SLC41A1 overexpressing SH-SY5Y cells after H2O2 treatment. d PM20D1 and SLC41A1 overexpression cytotoxicity in primary cultures. Data are presented as means ± SEM. *p < 0.05; **p < 0.01; ***p < 0.005; ****p < 0.0001; one-way ANOVA, post hoc Holm-Sidak’s multiple comparison test

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