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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Methylome and transcriptome analyses reveal insights into the epigenetic basis for the good survival of hypomethylated ER-positive breast cancer subtype

Fig. 6

Epigenetic activation of putative tumor suppressor genes in improving survival of ER-positive BRCA. a Forest plot for assesses of the 47 genes on survival in ER-positive BRCA (bars represent the 95% CI). b KEGG pathways enriched by the 47 genes. c Methylation differences in cg24319902 between hypo-ER-positive and hyper-ER-positive BRCA subgroups (p < 0.05). d Association between methylation level of cg24319902 and expression level of SFRP1. e Survival plot of SFRP1 expression with survival in ER-positive cancer. f Methylation differences in cg21383810 between hypo-ER-positive and hyper-ER-positive cancer (p < 0.05). g Association between methylation level of cg21383810 and expression level of WIF1. h Survival plot of WIF1 expression with survival in ER-positive cancer

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Clinical Epigenetics

ISSN: 1868-7083

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