Table 2 Univariate cox analysis for progression-free survival and overall survival for pediatric EPN_PF

Mo. subgroup (EPN_PFA vs. EPN_PFB)

8.012

1.815–35.371

0.006

10.854

1.446–81.465

0.020

5hmC subgroup (high vs. low)

3.438

1.367–8.646

0.009

3.030

1.192–7.702

0.020

Resection (STR vs. GTR)

1.338

0.602–2.972

0.475

1.445

0.634–3.292

0.381

Ki-67 index (≥ 20% vs. < 20%)

3.726

1.475–9.427

0.005

1.787

0.921–3.468

0.086

1q gain (yes vs. no)

2.666

1.086–6.548

0.032

3.148

1.283–7.722

0.012

Age, years (< 4 vs. 4–18)

1.567

0.678–3.618

0.293

1.376

0.580–3.262

0.469

Radiotherapy (yes vs. no)

0.695

0.281–1.717

0.430

0.477

0.197–1.159

0.102

Chemotherapy (yes vs. no)

0.839

0.334–2.112

0.710

0.226

0.052–0.985

0.053

Histology (WHO III vs. WHO II)

2.115

0.760–5.885

0.151

2.938

0.855–10.104

0.087

Gender (male vs. female)

1.416

0.530–3.783

0.487

1.015

0.400–2.577

0.975