Fig. 3

The DNA methylation signature for overall survival (OS) prediction of gastric cancer (GC) patients. a Kaplan-Meier estimate of the OS using the identified DNA methylation signature. GC patients were divided into low-risk (N = 181) or high-risk (N = 182) subgroup based on the median of risk score. The difference between the two curves was determined by the two-side log-rank test. b The distribution of risk score derived from the DNA methylation signature. c The distribution of GC patients’ survival status. The difference between the low-risk and high-risk subgroup was determined by chi-square test. d The methylation β value profile of the identified DNA methylation signature in the high-risk and low-risk subgroups