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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer

Fig. 4

PCR replicate positivity rates in positive specimens. a Frequency distribution of the number of PCR replicates positive for methylation in patients without neoplasia (n = 81) and with cancer (n = 136). Each assayed specimen generates a total of 9 PCR replicates, 3 for each gene. b In cases (cancer or no neoplasia) where only one replicate was positive, the proportion for each gene responsible for the positive result. FP false positive, TP true positive, TN true negative, FN false negative

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