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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Identification of DNA methylation signatures associated with poor outcome in lower-risk Stage, Size, Grade and Necrosis (SSIGN) score clear cell renal cell cancer

Fig. 5

AUROC analysis for CpGs involved with differentiating low SSIGN score ccRCC patients. a AUROC using the top five CpGs obtained from a stepwise recursive partitioning analysis performed on the TCGA-KIRC derived LTS-STS cohort (LTS = 19, STS = 9). Each AUC is the cumulative score of the inclusion of an additional CpG in the following order: cg24304972 (black), cg16108059 (red), cg14010015 (green), cg02966332 (blue), and cg02139853 (fuchsia). b AUROC using the top six CpGs obtained from a stepwise recursive partitioning analysis performed on the cohort 2 (LTS = 30, STS = 27). Each AUC is the cumulative score of the inclusion of an additional CpG in the following order: chr3:195489634 (black), chr9:137024923 (red), chr5:3591951 (green), chr12:52708570 (blue), chr5:80256046 (kaki), and chr12:129338403 (fuchsia)

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Clinical Epigenetics

ISSN: 1868-7083

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