Table 5 CpG sites selected for validation
From: Male obesity impacts DNA methylation reprogramming in sperm
CG site | UCSC RefGene name | CHR | Avg β value overweight/obese | Avg β value normal weight | Difference in β | No. of associated CG sites | p value |
|---|---|---|---|---|---|---|---|
cg24908198 | TP53AIP1 | 11 | 0.1823 | 0.2331 | 0.0508 | 2 | < 0.01 |
cg17859706 | SPATA21 | 1 | 0.5510 | 0.6140 | 0.0630 | 1 | < 0.01 |
cg00171166 | SOGA1 | 20 | 0.3411 | 0.3918 | 0.0507 | 1 | < 0.01 |
cg27576241 | ADAM15 | 1 | 0.1082 | 0.1334 | 0.0252 | 1 | < 0.01 |
cg05772935 | MAPK8IP3 | 16 | 0.7174 | 0.6112 | 0.1143 | 4 | < 0.01 |
cg17169982 | TBCD | 17 | 0.2941 | 0.3210 | 0.0269 | 1 | < 0.01 |
cg25398727 | XKR6 | 8 | 0.7814 | 0.6950 | − 0.0864 | 2 | < 0.01 |
cg18870054 | MISP | 19 | 0.5356 | 0.4688 | − 0.0668 | 3 | < 0.01 |
cg01098939 | AMZ1 | 7 | 0.8160 | 0.9008 | 0.0848 | 1 | < 0.001 |
cg18578876 | HCAR3 | 12 | 0.7496 | 0.8654 | 0.1158 | 1 | < 0.01 |