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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Sperm DNA methylation epimutation biomarker for paternal offspring autism susceptibility

Fig. 2

a DMR-associated gene categories. DMRs at a p value threshold p < 1e−05 are shown. b Autism case versus control DMR PCA. PCA for DMRs at p < 1e−05. The first two principal components used and samples color code index indicated. The underlying data are the RPKM read depth for all DMRs. c DMR-associated genes and autism. The paternal offspring autism-susceptible DMRs previously shown to correlate with autism and associated neurodegenerative disease are presented. DMR-associated genes from the current study were compared to genes associated with autism in the published literature using Pathway Studio software (Elsevier, Inc.). Those that were in common are depicted

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