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Table 1 Top DML-containing genes and mean methylation change values

From: Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice

Tissue

Gene

DMLs

Mean methylation (%)

SD

F1 Hippocampus

Tnxb

9

28.6

43.6

 

Ncor2

8

 − 35.4

51.1

 

Prdm16

8

 − 5.21

61.1

 

Zfhx3

8

 − 19.2

47.9

 

Gse1

7

 − 59.7

13.9

F1 Cortex

Tmem151b

8

55.1

8.5

 

Prdm16

7

 − 65.4

13.2

 

Epas1

6

68.7

11.7

 

Fhl1

6

 − 51.6

5.9

 

Gse1

6

 − 40.0

54.6

F0 Cortex

Camta1

9

 − 13.8

59.7

 

Grip1

7

 − 43.2

39.8

 

Cask

5

 − 42.4

54.1

 

Gdf1

5

 − 53.4

6.0

 

Mfsd12

5

60.2

11.3

  1. Mean methylation values (percent, exposed—control) for F1 and F0 brain regions. The mean methylation column represents the average change across all called DMLs for a given gene. Standard deviation represents the variability between DMLs within a gene