Table 3 Top 30 differentially methylated single CpG sites (DMSs) between NEC and non-NEC colon
chr | Start | End | p value | q value | meth.diff | feature.name | name2 | dist.to.feature | feature.strand | Prom | Exon | Intron | mydiff.CpGi.annot.members | mydiff.shores.annot.members | mydiff.enhancer.annot.members |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
chr17 | 11019015 | 11019015 | 1.20E−21 | 8.39 E−15 | 40.29664 | NM_001101387 | PIRT | − 180,915 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr2 | 86062716 | 86062716 | 2.67 E−17 | 9.34 E−11 | 32.23282 | NM_015425 | POLR1A | 43,440 | – | 0 | 0 | 1 | 0 | 0 | 0 |
chr4 | 115491856 | 115491856 | 5.48 E−16 | 1.28 E−09 | 40.79545 | NM_022569 | NDST4 | − 377,981 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr14 | 52272903 | 52272903 | 1.95 E−15 | 3.41 E−09 | 72.84615 | NM_001281469 | PTGDR | 5192 | + | 0 | 0 | 1 | 0 | 0 | 0 |
chr10 | 21066470 | 21066470 | 1.40 E−14 | 1.32 E−08 | 35.83795 | NM_001177483 | C10orf113 | 80,090 | – | 0 | 0 | 1 | 0 | 0 | 0 |
chr3 | 175224788 | 175224788 | 1.33 E−14 | 1.32 E−08 | 37.83784 | NR_046713 | NAALADL2-AS2 | 46,309 | – | 0 | 0 | 1 | 0 | 0 | 0 |
chr5 | 24263140 | 24263140 | 1.51 E−14 | 1.32 E−08 | 56.26401 | NR_131245 | C5orf17 | 311,794 | + | 0 | 0 | 0 | 0 | 0 | 0 |
chr4 | 58967547 | 58967547 | 2.02 E−14 | 1.57 E−08 | 38.96104 | NR_133941 | LINC02429 | − 16,735 | + | 0 | 0 | 0 | 0 | 0 | 0 |
chr2 | 79966760 | 79966760 | 3.05 E−14 | 2.14 E−08 | 55.40583 | NR_107047 | MIR8080 | − 100,178 | – | 0 | 0 | 1 | 0 | 0 | 0 |
chr4 | 22556420 | 22556420 | 3.43 E−14 | 2.18 E−08 | 45.32618 | NM_145290 | ADGRA3 | − 40,367 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr5 | 17911285 | 17911285 | 3.99 E−14 | 2.33 E−08 | 33.63636 | NR_134287 | LINC02223 | 104,013 | + | 0 | 0 | 1 | 0 | 0 | 0 |
chr2 | 119409733 | 119409733 | 4.60 E−14 | 2.47 E−08 | 53.94235 | NM_183240 | TMEM37 | − 22,137 | + | 0 | 0 | 0 | 0 | 0 | 0 |
chr20 | 38460167 | 38460167 | 9.79 E−14 | 4.89 E−08 | 42.20401 | NR_002986 | SNORA60 | 10,800 | + | 0 | 0 | 0 | 0 | 0 | 0 |
chr3 | 101804213 | 101804213 | 1.31 E−13 | 5.91 E−08 | 51.44188 | NM_001005474 | NFKBIZ | − 23,777 | + | 0 | 0 | 1 | 0 | 0 | 0 |
chr7 | 67694175 | 67694175 | 1.35 E−13 | 5.91 E−08 | 64.74501 | NR_120514 | LOC102723427 | − 326,078 | + | 0 | 0 | 0 | 0 | 0 | 0 |
chr6 | 121426895 | 121426895 | 1.44 E−13 | 5.94 E−08 | 63.50051 | NM_000165 | GJA1 | − 8682 | + | 0 | 0 | 0 | 0 | 0 | 0 |
chr12 | 101416276 | 101416276 | 1.81 E−13 | 7.02 E−08 | 42.5265 | NM_001301068 | ARL1 | − 8457 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr6 | 78594584 | 78594584 | 2.13 E−13 | 7.85 E−08 | 50.29663 | NM_001010844 | IRAK1BP1 | − 272,960 | + | 0 | 0 | 0 | 0 | 0 | 0 |
chr11 | 12359400 | 12359400 | 2.47 E−13 | 8.05 E−08 | 38.54167 | NM_018222 | PARVA | − 18,171 | + | 0 | 1 | 0 | 0 | 0 | 0 |
chr15 | 63678136 | 63678136 | 2.37 E−13 | 8.05 E−08 | 55.5917 | NR_034080 | USP3-AS1 | − 77,310 | – | 0 | 1 | 0 | 0 | 0 | 0 |
chr6 | 81046717 | 81046717 | 2.53 E−13 | 8.05 E−08 | 31.96195 | NM_017633 | TENT5A | 705,995 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr1 | 167097455 | 167097455 | 3.50 E−13 | 1.02 E−07 | 66.47619 | NM_001080426 | DUSP27 | 3367 | + | 0 | 0 | 1 | 0 | 0 | 0 |
chr15 | 81380112 | 81380112 | 4.30 E−13 | 1.20 E−07 | 44.66705 | NM_001080532 | TMC3 | − 5957 | – | 0 | 0 | 1 | 0 | 0 | 0 |
chr2 | 150152356 | 150152356 | 4.63 E−13 | 1.25 E−07 | 56.97802 | NR_146972 | LINC01817 | 104,652 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr6 | 167440526 | 167440526 | 6.28 E−13 | 1.47 E−07 | 47.95134 | NR_134591 | LOC105378127 | 32,265 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr16 | 63305874 | 63305874 | 7.40 E−13 | 1.67 E−07 | 40.34462 | NM_001796 | CDH8 | − 1E+06 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr10 | 99591101 | 99591101 | 8.02 E−13 | 1.70 E−07 | 60.53068 | NM_031212 | SLC25A28 | 29,364 | – | 0 | 0 | 0 | 0 | 0 | 0 |
chr5 | 22585518 | 22585518 | 7.92 E−13 | 1.70 E−07 | 50.73758 | NM_001364104 | CDH12 | 267,827 | – | 0 | 0 | 1 | 0 | 0 | 0 |
chr8 | 61783188 | 61783188 | 8.72 E−13 | 1.80 E−07 | 58.48694 | NR_039680 | MIR4470 | 68,402 | + | 0 | 0 | 0 | 0 | 0 | 0 |
chr19 | 53612831 | 53612831 | 1.15 E−12 | 2.24 E−07 | 51.38783 | NR_002938 | LOC284379 | − 9335 | – | 0 | 0 | 0 | 0 | 0 | 0 |