Developmental programming in human umbilical cord vein endothelial cells following fetal growth restriction

Clinical Epigenetics

Table 3 DNA methylation of each CpG position for the three highest significantly different expressed genes

Gene	CpG position	Methylation (%) Control (n = 8)	Methylation (%) FGR (n = 11)	p value
LGALS1	CpG1	15.88 ± 8.87	13.61 ± 9.44	0.60
	CpG2	10.71 ± 6.24	9.58 ± 7.30	0.73
	CpG3	11.16 (9.22–23.78)^†	14.80 (8.08–23.24)	0.86
	CpG4	8.63 ± 4.71^†	8.05 ± 5.32	0.82
FPR3	CpG1	93.55 ± 1.21	92.60 ± 1.24	0.11
FPR3	CpG2	96.15 ± 1.31	94.68 ± 2.14	0.10
NRM	CpG1	0.98 ± 0.31	1.72 ± 0.47	0.001
	CpG2	2.20 ± 0.53	2.21 ± 0.63	0.96
	CpG3	6.97 (2.21–10.71)	6.78 (6.03–10.30)	0.72
	CpG4	5.09 (3.67–10.31)	5.76 (4.39–8.63)	0.31
	CpG5	3.01 ± 0.88	2.89 ± 0.84	0.77
	CpG6	2.68 ± 0.89	3.09 ± 1.05	0.38

Data expressed as mean ± SD tested with independent t test or median (min–max) tested with Mann–Whitney. ^†7 instead of eight samples

ISSN: 1868-7083