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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Micro-RNA-125a mediates the effects of hypomethylating agents in chronic myelomonocytic leukemia

Fig. 2

miR-125a expression is decreased in primary CMML patient specimens. a The box plots show the relative miR-125a, miR-150, and miR-26a expression levels in 36 CMML patient specimens compared to six CD34+ HSPCs. b The relative expression level of miR-125a in 36 CMML patients compared to six whole BM specimens of healthy donors and patients with lymphatic diseases without BM affection is displayed. The graphs denote the miR expression normalized to a calibrator, set to 1 (U937 for miR-125a and miR-26a; GDM-1 for miR-150). Differences between the groups were assessed with the Mann–Whitney U test. CMML, chronic myelomonocytic leukemia; BM, bone marrow; HSPCs, hematopoietic stem and progenitor cells

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