Table 2 Clinical characteristics at baseline in the DACHS study

Sex, n (%)

 Women

910 (41.2)

 Men

1296 (58.8)

Age at diagnosis, n (%)

 33 ≤–< 55 years

238 (10.8)

 55 ≤–< 65 years

479 (21.7)

 65 ≤–< 75 years

776 (35.2)

 75 ≤–≤ 96 years

713 (32.3)

Tumor stage, n (%)*

 I

400 (18.2)

 II

760 (34.6)

 III

726 (33.1)

 IV

309 (14.1)

Leukocyte composition, Median (IQR)^#

 CD4 + T cells

0.12 (0.07, 0.17)

 CD8 + T cells

0.03 (0.004, 0.06)

 NK cells

0.07 (0.04, 0.11)

 B cells

0.04 (0.03, 0.06)

 Monocytes

0.08 (0.06, 0.10)

 Granulocytes

0.65 (0.56, 0.74)

Charlson comorbidity index, n (%)

 0 (no comorbidity)

1282 (58.1)

 1 (mild comorbidity)

479 (21.7)

 2 (moderate comorbidity)

264 (12.0)

 3+ (severe comorbidity)

182 (8.2)

Tumor sub-site, n (%)*

 Proximal colon^†

796 (36.1)

 Distal colon^‡

738 (33.5)

 Rectum

670 (30.4)

BMI at diagnosis, n (%)*

–

 < 25 kg/m²

834 (38.0)

 25 ≤–< 30 kg/m²

932 (42.4)

 ≥ 30 kg/m²

430 (19.6)

Alcohol consumption, n (%)*

–

 Abstainer

380 (17.3)

 Female: < 20 g/day; Male: < 40 g/day

1559 (70.9)

 Female: ≥ 20 g/day; Male: ≥ 40 g/day

260 (11.8)

Smoking status, n (%)*

 Never

907 (41.1)

 Former

948 (43.0)

 Current

350 (15.9)