Table 2 Canonical pathways among total AGM DMG
Ingenuity canonical pathways | − log(p value) | Genes |
|---|---|---|
Neuregulin signaling | 3.34 | RPS6KB1, ITGA3, HSP90AB1, GRB2, CRKL, PRKCB, EGFR, PRKCA |
Nitric oxide signaling in the cardiovascular system | 3.33 | PDE2A, HSP90AB1, GUCY1A3, GRB2, PRKAR1B, PIK3CD, ARG2, PRKCB, PRKCA |
Caveolar-mediated endocytosis signaling | 3.14 | ITGA3, ITGA7, ACTC1, ITGB7, COPG1, EGFR, PRKCA |
Cholecystokinin/gastrin-mediated signaling | 2.88 | PTK2, GRB2, CREM, PLCB1, IL1F10, PRKCB, EGFR, PRKCA |
3-phosphoinositide biosynthesis | 2.64 | PLPP6, ITPK1, TNS3, PTPRJ, PPP1R7, GRB2, DOT1L, PIK3CD, MTMR7, EGFR, SACM1L |
HER-2 signaling in breast cancer | 2.59 | GRB2, PIK3CD, PARD3, ITGB7, PRKCB, EGFR, PRKCA |
Gap junction signaling | 2.59 | DBN1, GUCY1A3, GRB2, PRKAR1B, PLCB1, PIK3CD, ACTC1, PRKCB, EGFR, PRKCA |
UVB-induced MAPK signaling | 2.58 | RPS6KB1, GRB2, PIK3CD, PRKCB, EGFR, PRKCA |
HGF signaling | 2.54 | ETS1, PTK2, ITGA3, GRB2, CRKL, PIK3CD, PRKCB, PRKCA |
Superpathway of inositol phosphate compounds | 2.53 | PLPP6, ITPK1, TNS3, PTPRJ, PPP1R7, GRB2, DOT1L, PLCB1, PIK3CD, MTMR7, EGFR, SACM1L |