Skip to main content
Fig. 7 | Clinical Epigenetics

Fig. 7

From: DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections

Fig. 7

Validation of methylation changes in an independent cohort of 17 Indian rhesus macaques. Comparison of DNA methylation levels at the 17 selected probe sites in the validation cohort by sequencing CD4 + T cells from a LN and b blood. *p < 0.05, Mann–Whitney, **p < 0.01, Mann–Whitney. c LN and d blood multidimensional scaling showing clustering of validation animals for all CpG included in the 16 bisulfite pyrosequencing assays. Symbols represent individual animals that are uninfected (red circles, n = 4), infected and viremic (green triangles, n = 6) or SIV controllers (blue squares, n = 7). Ellipses depict 50% confidence intervals. Kruskal stress is 0.14 and 0.13 for LN and blood, respectively

Back to article page