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Fig. 2 | Clinical Epigenetics

Fig. 2

From: DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections

Fig. 2

Time and tissue-specific changes in DNA methylation of CD4 + T cells following SIV infection. a Heatmaps show methylation levels for each of the differentially methylated probes (DMP) in the rows and individual animals in the columns for MAC LN and blood. Blue indicates highly methylated and yellow indicates low levels of methylation after z scale normalization per probe. LN lymph node. a Acute phase (day14). The height of each of the heatmaps is proportional to the number of differentially methylated probes. b Venn diagram showing the number (and percentages in parentheses) of overlapping DMG in the different conditions for MAC. c Heatmaps showing methylation levels for AGM as described for MAC above. d Venn diagram showing the overlap in DMG for AGM as described for MAC above. e Venn diagram showing the overlap in DMG found in both species. AGM African green monkeys (sabaeus), MAC Chinese rhesus macaque. The number of animals included is the same as in Fig. 1

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Clinical Epigenetics

ISSN: 1868-7083

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