Fig. 4
From: Circulating cell-free nucleosomes as biomarker for kidney transplant rejection: a pilot study
Diagnostic performance of total CCFN (H3) to discriminate from the stable situation (day 30 and day 180). a ROC curve and b. Sensitivity (black) and specificity (white) depicted over the observed range of CCFN concentrations. Reported sensitivity and specificity correspond to a cutoff of 3687 ng/mL serum. PPV and NPV are based on an incidence of AR of 15%. AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value