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Fig. 5 | Clinical Epigenetics

Fig. 5

From: 5-Hydroxymethylation highlights the heterogeneity in keratinization and cell junctions in head and neck cancers

Fig. 5

Protein expression level of MMP2 in 2 HPV(−) and 3 HPV(+) HNSCC cell lines. a Scatterplot showing a correlation between log gene expression and log 5hmC of MMP2 gene. HPV(−) samples were concentrated near the top right corner, indicating that both their gene expression and 5hmC coverage were higher compared with HPV(+) samples. b Zymogram and c immunoblot indicated the secreted and intracellular level of MMP2 protein respectively. d Dot plot showing the mRNA level of MMP2 with two replicates. After removing the HPV(+) oral cavity cell line, which is an outlier, Wilcoxon signed-rank test showed a p value = 0.34

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Clinical Epigenetics

ISSN: 1868-7083

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