|
Gene ID
|
Control %
|
Patient %
|
Difference
|
P value
|
Q value
|
|---|
|
MEGF6
|
55
|
17
|
− 38
|
1.12 × 10–11
|
4.63 × 10–9
|
|
CD6
|
41
|
3
|
− 38
|
1.90 × 10–16
|
1.02 × 10–13
|
|
KIF1A
|
50
|
14
|
− 36
|
1.83 × 10–10
|
7.16 × 10–8
|
|
MEGF11
|
84
|
52
|
− 32
|
6.09 × 10–12
|
2.54 × 10–9
|
|
TMCO3
|
94
|
61
|
− 33
|
3.28 × 10–9
|
1.20 × 10–6
|
|
LINC00664
|
53
|
95
|
+ 42
|
2.95 × 10–15
|
1.50 × 10–12
|
|
LOC642423
|
43
|
84
|
+ 41
|
2.60 × 10–14
|
1.24 × 10–11
|
|
KCNK10
|
54
|
93
|
+ 39
|
2.92 × 10–17
|
1.60 × 10–14
|
|
IDUA
|
59
|
95
|
+ 36
|
1.21 × 10–13
|
5.58 × 10–11
|
|
FAM182B
|
0
|
34
|
+ 34
|
8.99 × 10–16
|
4.71 × 10–13
|
- Gene-associated cytosine significance values were calculated using a Fisher’s test. For each cytosine, there is also corresponding genomic location, the average methylation percentages for the control subjects and ME/CFS patients, with differences (− hypo-methylated, + is hyper-methylated). Corresponding P and Q values are indicated. The full dataset is available in Additional file 1: Excel file ‘MethylKit_Gene_Full’
