Table 6 Top hypo-methylated (5 of 43) and hyper-methylated (5 of 41) individual cytosines associated with gene bodies (exons/introns)
Gene ID | Control % | Patient % | Difference | P value | Q value |
|---|---|---|---|---|---|
MEGF6 | 55 | 17 | − 38 | 1.12 × 10–11 | 4.63 × 10–9 |
CD6 | 41 | 3 | − 38 | 1.90 × 10–16 | 1.02 × 10–13 |
KIF1A | 50 | 14 | − 36 | 1.83 × 10–10 | 7.16 × 10–8 |
MEGF11 | 84 | 52 | − 32 | 6.09 × 10–12 | 2.54 × 10–9 |
TMCO3 | 94 | 61 | − 33 | 3.28 × 10–9 | 1.20 × 10–6 |
LINC00664 | 53 | 95 | + 42 | 2.95 × 10–15 | 1.50 × 10–12 |
LOC642423 | 43 | 84 | + 41 | 2.60 × 10–14 | 1.24 × 10–11 |
KCNK10 | 54 | 93 | + 39 | 2.92 × 10–17 | 1.60 × 10–14 |
IDUA | 59 | 95 | + 36 | 1.21 × 10–13 | 5.58 × 10–11 |
FAM182B | 0 | 34 | + 34 | 8.99 × 10–16 | 4.71 × 10–13 |