Table 5 Top hypo-methylated (5 out of 17) and top hyper-methylated (5 out of 14) methylated fragment-associated gene bodies (exons/introns)
Gene ID | CpGs | Control % | Patient % | Difference | P value | F test value |
|---|---|---|---|---|---|---|
SARDH | 3 | 88 | 64 | − 24 | 6.52 × 10–3 | F(1,14) = 10.19 |
MAST4 | 4 | 82 | 61 | − 21 | 4.72 × 10–3 | F(1,14) = 11.26 |
GRAMD4 | 4 | 64 | 44 | − 20 | 4.80 × 10–2 | F(1,13) = 4.76 |
GNG7 | 7 | 64 | 45 | − 19 | 2.94 × 10–2 | F(1,17) = 5.66 |
RP11-566K11.2 | 7 | 46 | 28 | − 18 | 6.01 × 10–2 | F(1,15) = 18.70 |
ZNF714 | 6 | 12 | 42 | + 30 | 1.12 × 10–2 | F(1,16) = 8.22 |
DNAJB13 | 5 | 41 | 69 | + 28 | 4.57 × 10–4 | F(1,15) = 19.91 |
COX19 | 6 | 11 | 32 | + 21 | 1.96 × 10–2 | F(1,15) = 6.82 |
CARD8 | 3 | 77 | 98 | + 21 | 7.06 × 10–4 | F(1,13) = 19.44 |
C8orf31 | 9 | 43 | 64 | + 21 | 4.75 × 10–2 | F(1,13) = 4.79 |