Table 4 Genes linked to promoter regions associated with the top differentially methylated individual cytosines (5 of 31 hypo- and 5 of 14 hyper-methylated)
Gene ID | Control % | Patient % | Difference | P value | Q value |
|---|---|---|---|---|---|
LOC339166 | 76 | 34 | − 42 | 3.94 × 10–12 | 1.67 × 10–9 |
LOC339166 | 74 | 32 | − 40 | 1.96 × 10–11 | 7.97 × 10–9 |
LOC339166 | 75 | 35 | − 39 | 9.19 × 10–11 | 3.63 × 10–8 |
LOC339166 | 71 | 35 | − 35 | 4.71 × 10–9 | 1.70 × 10–6 |
LOC339166 | 75 | 39 | − 35 | 8.62 × 10–9 | 3.05 × 10–6 |
FANK1 | 19 | 48 | + 28 | 2.31 × 10–12 | 9.82 × 10–10 |
CILP2 | 30 | 51 | + 23 | 1.94 × 10–4 | 3.40 × 10–2 |
A2M-AS1 | 13 | 32 | + 21 | 4.93 × 10–5 | 1.05 × 10–2 |
SPIN2B | 20 | 40 | + 20 | 2.45 × 10–5 | 5.58 × 10–3 |
MT1M | 12 | 29 | + 18 | 1.21 × 10–4 | 2.29 × 10–2 |