Fig. 5

Overlaps observed between the genes identified in this New Zealand study and previously published studies. a Bar plot showing the percentage of genes identified in the New Zealand study described here that overlap with previous published work that assessed the methylome of ME/CFS patients compared to healthy controls. a Bar A is the Trivedi et al. 2018 study [9], bar B is de Vega et al. [8], bar C is de Vega et al. [7], bar D is Brenu et al. [6], and bar E is Herrera et al. [10]. A summary of the genes found to be overlapping with each study is provided in Additional file 1: Excel file ‘Genelist_Overlaps’. b Bar plots showing the number of the 122 genes identified in the New Zealand study that overlapped with: ‘(A + B)’—both the Trivedi et al. [9] and de Vega et al. [8] studies; ‘A only’—Trivedi et al. [9], ‘B only’—de Vega et al. [8]. None of the overlaps between our New Zealand study and the de Vega et al. [7] (bar C in Fig. 5a) were unique to that study, but were also found in the other two studies [8, 9]