From: DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures
 | KORA F4 (N = 1662) | LOLIPOP (N = 2805) | YFS (N = 176) | NFBC1966 (N = 771) |
---|---|---|---|---|
Age (years) | 61.0 (8.9) | 51.4 (10.1) | 44.2 (3.3) | 31.0 (0.3) |
Sex = male | 49.0% | 68.0% | 37.5% | 43.7% |
BMI (kg/m2)a | 28.1 (4.8) | 27.7 (4.4) | 25.9 (4.5) | 24.4 (3.7) |
Current smokers | 14.4% | 8.9% | 16.5% | 26.2% |
Ex-smokers | 41.5% | 8.7% | 25.6% | 19.2% |
Never smokers | 44.1% | 82.4% | 58.0% | 53.3% |
Alcohol consumption (g/day) | 15.5 (20.3) | 6.38 (14.2) | 0.716 (0.9)b | 8.7 (14.3) |
C-reactive protein (mg/l) | 2.5 (5.2) | 4.2 (7.2) | 1.4 (2.4) | 1.85 (3.3) |
HDL-C (mmol/l) | 1.7 (0.4) | 1.3 (0.3) | 1.7 (0.4) | 1.7 (0.5) |
LDL-C (mmol/l) | 2.1 (0.6) | 1.9 (0.6) | 2.1 (0.6) | 2.0 (0.7) |
Total cholesterol (mmol/l) | 5.7 (1.0) | 4.9 (1.1) | 5.3 (1.0) | 5.5 (1.4) |
Total TGc (mmol/l) | 1.6 (0.8) | 1.5 (0.7) | 1.2 (0.6) | 1.2 (0.7) |
VLDL-TG (mmol/l) | 1.1 (0.8) | 0.9 (0.6) | 0.7 (0.6) | 0.7 (0.5) |
Total FA (mmol/l) | 14.5 (2.4) | 12.5 (3.0) | 12.9 (2.3) | 13.4 (3.5) |
Hypertensione | 45.5% | 38.0% | 19.3% | 16.7% |
Hospitalized myocardial infarctione | 3.6% | 3.9% | 0.0% | 0.0% |
Intake of lipid-lowering drugs | 16.2% | NAd | 4.0% | 0.0% |