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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs

Fig. 4

Effect of chronic morphine treatment on PRC2 repressive epigenetic complex. RNA-seq and H3K27me3 ChIP-seq track transitions enriched at promoter level, for PRC2 complex subunits Suz12, Ezh2, Eed, Rbbp4 and Rbbp7. CpG features track was composed by CpG islands in green, shores in light blue, shelfs in dark blue and open sea in grey. Red boxes point out the enrichment and gene expression change location

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