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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs

Fig. 1

Effect of chronic morphine treatment on H3K27me3 in mESCs. a Scheme of mESCs culture and 24 h morphine treatment for in vitro epigenetic changes determination. Representative image of treated and untreated mESCs is also shown. Scale bar = 400 µm. b Western blot analysis of H3K27me3 after morphine treatment for 24 h. β-actin was used as loading control. Sample size n = 5

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