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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Smoking-related changes in DNA methylation and gene expression are associated with cardio-metabolic traits

Fig. 3

Schematic overview of the mediation analyses. We used mediation analysis to test the mediation effect of gene expression in the association between smoking and cardio-metabolic traits (A1 and A2). Furthermore, we tested the mediation effect of DNA methylation in the associations between smoking and gene expression (B1 and B2) and the mediation effect of DNA methylation in the association between smoking and cardio-metabolic traits (C1 and C2)

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Clinical Epigenetics

ISSN: 1868-7083

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