Fig. 3

The result of first clustering analysis and heat map of the methylation pattern focusing on the 809 probes at 77 known iDMRs. The patients with SRS, TS14, and PWS are shown in pink, brown, and blue boxes, respectively. The vertical axis indicates the 809 probes at the 77 known iDMRs. The representative iDMRs are shown in gray boxes. SRS Silver–Russell syndrome, TS14 Temple syndrome, PWS Prader–Willi syndrome, iDMRs imprinting-associated differentially methylated regions