Fig. 1

available at the respective time points. p values shown were obtained with paired t tests and represent the comparison with the previous time point. *p value ≤ 0.05, **p value ≤ 0.01, ***p value ≤ 0.001. Tests were not performed to compare the last PICU day with the previous time point, in view of the variability of the last day (which also was equal to day 3, day 5 or day 7 for some of the patients). Δd0: β value day 0 minus β value day 0, Δd3: β value day 3 minus β value day 0, Δd5: β value day 5 minus β value day 0, ∆d7: β value day 7 minus β value day 0, ΔLd: β value last PICU day minus β value day 0