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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Identification of fetal unmodified and 5-hydroxymethylated CG sites in maternal cell-free DNA for non-invasive prenatal testing

Fig. 2

Correlation of the reference fetal fraction and SeqFF prediction from a uTOP-seq and b hmTOP-seq data indicates the enrichment of cffDNA in maternal cfDNA mixture. Dashed line indicates linear regression. hmTOP-seq samples of shallow sequencing (on average 2.5 million (M) raw reads) are indicated with red circles and were not used in the estimation of Pearson correlation

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