| |
AgeAccelGrim
|
p value
|
DNAmPAI1AdjAge
|
p value
|
|---|
|
Age group
| | | | |
|
Middle-aged (< 60 years)
|
1.16 [1.1, 1.35]
|
0.046
|
1.0003[1.0001, 1.0004]
|
< 0.001
|
|
Elderly (≥ 60 years)
|
1.07 [0.94, 1.23]
|
0.311
|
1.0001 [1, 1.0002]
|
0.023
|
|
Living area
| | | | |
|
Rural
|
1.05 [0.93, 1.19]
|
0.465
|
1.0001 [1, 1.0002]
|
0.047
|
|
Urban
|
1.06 [0.98, 1.15]
|
0.123
|
1.0004 [1.0002, 1.0005]
|
< 0.001
|
|
Sex
| | | | |
|
Female
|
1.15 [1, 1.33]
|
0.047
|
1.0001 [1, 1.0003]
|
0.007
|
|
Male
|
1.06 [0.92, 1.21]
|
0.446
|
1.0002 [1.0001, 1.0004]
|
< 0.001
|
|
Smoking
| | | | |
|
Never smoker
|
1.2 [1.05, 1.37]
|
0.007
|
1.0002 [1.0001, 1.0003]
|
< 0.001
|
|
Former smoker
|
0.9 [0.71, 1.14]
|
0.384
|
1.0001 [0.9999, 1.0004]
|
0.210
|
|
Current smoker
|
1.21 [0.95, 1.54]
|
0.123
|
1.0004 [1.0002, 1.0007]
|
< 0.001
|
|
Alcohol drinking
| | | | |
|
Never drinker
|
1.19 [1.02, 1.39]
|
0.021
|
1.0001 [1, 1.0002]
|
0.020
|
|
Regular drinker
|
1.03 [0.9, 1.19]
|
0.655
|
1.0002 [1.0001, 1.0004]
|
< 0.001
|
- Data are presented as Odds ratio [95% confidence interval] of metabolic syndrome. AceAccelGrim, accelerated DNAm GrimAge; DNAmPAIAdjAge, age-adjusted DANmPAI1; chronological age, sex, regional area and DNAmPACKYRS were included in the multiple linear regression
