Table 3 Odds ratios for metabolic syndrome for accelerated GrimAge and age-adjusted DNAmPAI1

Age group

 Middle-aged (< 60 years)

1.16 [1.1, 1.35]

0.046

1.0003[1.0001, 1.0004]

< 0.001

 Elderly (≥ 60 years)

1.07 [0.94, 1.23]

0.311

1.0001 [1, 1.0002]

0.023

Living area

 Rural

1.05 [0.93, 1.19]

0.465

1.0001 [1, 1.0002]

0.047

 Urban

1.06 [0.98, 1.15]

0.123

1.0004 [1.0002, 1.0005]

< 0.001

Sex

 Female

1.15 [1, 1.33]

0.047

1.0001 [1, 1.0003]

0.007

 Male

1.06 [0.92, 1.21]

0.446

1.0002 [1.0001, 1.0004]

< 0.001

Smoking

 Never smoker

1.2 [1.05, 1.37]

0.007

1.0002 [1.0001, 1.0003]

< 0.001

 Former smoker

0.9 [0.71, 1.14]

0.384

1.0001 [0.9999, 1.0004]

0.210

 Current smoker

1.21 [0.95, 1.54]

0.123

1.0004 [1.0002, 1.0007]

< 0.001

Alcohol drinking

 Never drinker

1.19 [1.02, 1.39]

0.021

1.0001 [1, 1.0002]

0.020

 Regular drinker

1.03 [0.9, 1.19]

0.655

1.0002 [1.0001, 1.0004]

< 0.001