Control | MetS | p value | |
---|---|---|---|
Age, years | 59.74 (8.21) | 62.25 (8.49) | < 0.001 |
DNAmAge (years) | |||
Pan-tissue | 62.99 (7.62) | 62.05 (7.53) | 0.262 |
Hannum | 66.46 (7.60) | 67.49 (7.21) | 0.204 |
PhenoAge | 56.02 (8.30) | 56.50 (7.51) | 0.569 |
GrimAge | 65.05 (7.16) | 67.21 (6.52) | 0.004 |
SEM | 2.89 (0.02) | 2.88 (0.02) | 0.710 |
DNAm-based Protein surrogates | |||
DNAm ADM | 347.94 (19.71) | 353.19 (22.35) | 0.026 |
DNAm B2M | 1695400.53 (118063.24) | 17164680.23 (111301.02) | 0.093 |
DNAm CystatinC | 657922.87 (30767.76) | 663421.07 (33629.34) | 0.125 |
DNAm GDF15 | 778.64 (114.38) | 792.13 (110.96) | 0.275 |
DNAm Leptin | 6425.81 (3842.37) | 6812.72 (3994.74) | 0.371 |
DNAm PAI1 | 18346.47 (3169.11) | 19880.95 (2926.86) | < 0.001 |
DNAm TIMP1 | 34309.52 (1239.02) | 34686.02 (1147.70) | 0.004 |
DNAm Packyrs | 23.57 (12.70) | 23.88 (12.05) | 0.813 |