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Table 1 Sample characteristics in HIV-positive participants

From: DNA methylation mediates the effect of cocaine use on HIV severity

 

Baselinea

Follow-up (time of blood collection)b

Sample size

1435

875

 Age [mean (sd)]

48.8 (8.1)

51.5 (7.7)

 Sex

  

  Male

1399 (97.5%)

861 (98.4%)

  Female

36 (2.5%)

14 (1.6%)

 Race

  

  Caucasian

290 (20.2%)

84 (9.6%)

  African American

964 (67.2%)

726 (83.0%)

  Others

181 (12.6%)

65 (7.4%)

 Persistent cocaine use status

  

  Persistent cocaine use

 

265 (30.3%)

  Non-cocaine use

 

202 (23.1%)

 Cocaine use at baseline (%)

  

  Have never tried

555 (38.7%)

 

  No use in the last year

540 (37.6%)

 

  Less than once a month

122 (8.5%)

 

  1–3 times a month

103 (7.2%)

 

  1–3 times a week

39 (2.7%)

 

  ≥ 4 times a week

76 (5.3%)

 

 Cigarette smoking

762 (53.1%)

521 (59.5%)

 VACS index

30.0 (19.1)

 

Average VACS index after blood collection [mean (sd)]

 

39.20 (22.4)

 CD4+ count [mean (sd)]

418.7 (273.0)

440.02 (289.1)

 log10 viral load [mean (sd)]

3.1 (1.2)

2.74 (1.2)

 Antiviral medication adherence (%)

1117 (77.8%)

666 (76.1%)

  1. VACS index: Veteran Aging Cohort Study index
  2. aSamples at baseline for the survival analysis
  3. bA subset of samples at the time of blood collection with DNA methylation measurements