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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Reduced mitochondrial D-loop methylation levels in sporadic amyotrophic lateral sclerosis

Fig. 5

D-loop region methylation (a) and mtDNA copy number (b) in controls (n = 51), SOD1-ALS (n = 14), C9orf72-ALS (n = 13), and sporadic ALS patients (n = 36). Data are expressed as means ± SD. Statistical analysis was performed by means of ANCOVA, using age at sampling and sex as covariates. Only p values that survived correction for multiple comparisons are shown. *p < 0.05; **p < 0.01; ***p < 0.001

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