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Table 1 Participant characteristics

From: DNA methylation of FKBP5 in South African women: associations with obesity and insulin resistance

  Normal weight (n=27) Obese (n=27) P value
DEMOGRAPHIC AND LIFESTYLE FACTORS
Age (years) 24 (22-26) 28 (24-36) 0.004
Ethnicity
Blacka 14 (51.9) 14 (51.9)  
SES 16.8 (11.6-22.6) 20.1 (10.6-23.1) 0.843
Smoking (yes)a 7 (25.9) 7 (25.9) 0.936
Alcohol consumption (g) 4.7 (0-24.6) 3.8 (0-16.1) 0.854
BODY COMPOSITION
BMI (kg/m2) 22.9 (21.7-23.7) 38.3 (34.3-41.6) <0.001
Fat (%) 29.7 (25.9-35.1) 47.0 (43.5-49.6) <0.001
BODY FAT DISTRIBUTION
Waist circumference (cm) 78.3 (74.0-82.0) 112.5 (102.6-118.5) <0.001
GSAT (kg) 4.6 (4.0-5.2) 5.9 (5.4-6.5) 0.001
ASAT (cm2) 169.7 (134.7-225.6) 558.2 (480.2-620.3) <0.001
VAT (cm2) 54.3 (42.6-77.2) 107.7 (80.3-173.7) <0.001
METABOLIC PARAMETERS
Fasting Glucose (mmol/L) 4.4 (4.1-4.6) 4.5 (4.4-4. 7) 0.027
Fasting Insulin (mU/L) 5.1 (3.5-8.5) 12.5 (7.1-16.9) 0.001
HOMA-IR 0.9 (0.7-1.7) 2.5 (1.1-3.3) <0.001
SI (·10-4 min-1/[μU/ml]) 4.1 (1.4-6.2) 1.8 (1.0-3.6) 0.011
C-reactive protein (mg/l) 1.2 (0.6-3.8) 7.9 (3.4-8.7) <0.001
Adiponectin (ng/ml) 6.5 (4.1-9.5) 3.5 (2.1-5.8) <0.001
Leptin (ng/ml) 15.2 (7.8-20.5) 59.0 (47.9-66.2) <0.001
  1. Data expressed as the median (25th–75th percentile) or as acount (percentage)
  2. Abbreviations: BMI body mass index, GSAT gluteal subcutaneous adipose tissue, HOMA-IR Homeostatic model of insulin resistance, SAT subcutaneous adipose tissue, SES socioeconomic score, SI insulin sensitivity index, VAT visceral adipose tissue