Characteristics | Discovery sample | Replication sample | ||||
---|---|---|---|---|---|---|
Non-HBP | HBP | P | non-HBP | HBP | P | |
No. of participants | 1389 | 1109 | - | 776 | 995 | - |
Age, years | 50.3 ± 9.3 | 55.7 ± 8.9 | < 0.001 | 59.6 ± 12.0 | 63.5 ± 12.0 | < 0.001 |
Sex, men n (%) | 430 (31.0) | 532 (48.0) | < 0.001 | 449 (47.0) | 507 (40.1) | 0.004 |
Education, high school or above n (%) | 296 (21.3) | 211 (19.0) | 0.158 | 562 (46.9) | 750 (42.5) | 0.143 |
Current smoking, n (%) | 281 (20.2) | 301 (27.1) | < 0.001 | 324 (40.0) | 318 (50.5) | < 0.001 |
Current drinking, n (%) | 199 (14.3) | 266 (24.0) | < 0.001 | 225 (42.5) | 250 (47.4) | 0.077 |
Body mass index, kg/m2 | 23.99 ± 3.30 | 25.78 ± 3.78 | < 0.001 | 22.51 ± 3.36 | 24.58 ± 3.59 | < 0.001 |
Fasting glucose, mmol/L | 5.15 ± 1.04 | 5.70 ± 1.59 | < 0.001 | 5.33 ± 1.82 | 6.31 ± 2.54 | < 0.001 |
Total cholesterol, mmol/L | 5.09 ± 1.52 | 5.38 ± 1.99 | < 0.001 | 4.68 ± 1.00 | 5.04 ± 1.12 | < 0.001 |
Triglycerides, mmol/L | 1.28 ± 1.40 | 1.69 ± 1.77 | < 0.001 | 1.52 ± 1.24 | 1.88 ± 4.60 | 0.017 |
LDL-cholesterol, mmol/L | 2.92 ± 0.74 | 3.09 ± 0.78 | < 0.001 | 3.11 ± 1.00 | 3.02 ± 0.96 | 0.053 |
HDL-cholesterol, mmol/L | 1.55 ± 0.48 | 1.45 ± 0.39 | < 0.001 | 1.35 ± 0.34 | 1.31 ± 0.39 | 0.018 |