Fig. 6
From: Epigenetic silencing of miR-342-3p in B cell lymphoma and its impact on autophagy
miR-342-3p downregulating DNMT1 and re-expression of E-CAD by promoter demethylation in SU-DHL-16 cells. a M- and U-MSP showed E-CAD was completely methylated in SU-DHL-16 cells. b The expression of DNMT1 decreased upon overexpression of miR-342-3p by qRT-PCR. c Effect of overexpression of miR-342-3p on the methylation status of E-CAD promoter by MSP. d The expression of E-CAD increased upon overexpression of miR-342-3p by qRT-PCR. Data of qRT-PCR were normalized to negative scramble control as 1. Columns represent mean +/− 1SD from three experiments in triplicate