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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Epigenetic silencing of miR-342-3p in B cell lymphoma and its impact on autophagy

Fig. 1

Methylation of EVL/MIR342 in healthy normal controls and NHL cell lines. a Direct sequencing of M-MSP products from enzymatically methylated positive control DNA showed complete bisulfite conversion and MSP specificity. b, c Results of both M- and U-MSP showed absence of EVL/MIR342 methylation in healthy normal controls, including normal peripheral blood buffy coats (P1-P10) (b) and normal tonsil tissues (T1–T11) (c). d In lymphoma cell lines, M- and U-MSP showed that EVL/MIR342 was completely methylated (MM) in SU-DHL-16, partially methylated (MU) in JEKO-1, GRANTA-519, SU-DHL-6, and KARPAS-299, and completely unmethylated (UU) in MINO, REC-1, SP-53, SU-DHL-1, and SUP-T1

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