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Table 2 Differentially methylated genes. Gene regions with > 20 percent points difference in methylation ratio, between least methylated sample to most methylated sample along with fold change differences are listed. Hyper-methylated target region of those genes are shown in bold

From: Assessment of tumor suppressor promoter methylation in healthy individuals

Gene name Gene capture region Min. methylation ratio Max. methylation ratio Difference in methylation ratio Fold change
GAS7 chr17: 10199716 - 10200316 0.2670 0.9332 0.6662 3.4951
ELAC2 chr17: 13019069 - 13019845 0.4581 0.8332 0.3751 1.8188
GSTM1 chr1: 109686327 - 109687046 0.6438 1.0000 0.3562 1.5533
THBS1 chr15: 39579298 - 39579871 0.4671 0.7885 0.3214 1.6881
CIITA chr16: 10874982 - 10875928 0.2511 0.5577 0.3066 2.221
RASSF1 chr3: 50339388 - 50340021 0.1786 0.4720 0.2934 2.6428
CHN1 chr2: 174846842 - 174848034 0.2141 0.5074 0.2933 2.3699
MSH2 chr2: 47401613 - 47402319 0.5897 0.8734 0.2838 1.4811
PALB2 chr16: 23642511 - 23643136 0.6333 0.9134 0.2801 1.4423
RUNX3 chr1: 24964233 - 24965550 0.3920 0.6479 0.2559 1.6528
TP63 chr3: 189789769 - 189790448 0.6612 0.9059 0.2446 1.3701
PDCD1LG2 chr9: 5510022 - 5511326 0.3182 0.5511 0.2330 1.7319
AIP chr11: 67481632 - 67482276 0.6716 0.9002 0.2286 1.3404
GPC3 chrX: 133986729 - 133987434 0.5842 0.8036 0.2194 1.3756
AIP chr11: 67482202 - 67482880 0.1035 0.3214 0.2180 3.1053
GSTP1 chr11: 67581895 - 67582976 0.2673 0.4834 0.2162 1.8085
AIP chr11: 67481257 - 67481869 0.7857 1.0000 0.2143 1.2728
XPA chr9: 97698585 - 97699193 0.6991 0.9130 0.2139 1.306
APC chr5: 112736082 - 112736959 0.6361 0.8479 0.2118 1.333
CTCFL chr20: 57524096 - 57527440 0.6554 0.8663 0.2109 1.3218
CASP8 chr2: 201259179 - 201260169 0.3698 0.5799 0.2102 1.5681
ZNF668 chr16: 31064314 - 31065859 0.4513 0.6584 0.2070 1.4589
-- -- -- -- -- --
RABEP1 chr17: 5281240 - 5283045 0.0415 0.1033 0.0618 2.4902
AIP chr11: 67482382 - 67483805 0.0517 0.1229 0.0712 2.3783
RASSF1 chr3: 50338258 - 50339618 0.0976 0.2178 0.1202 2.2322
FOXO4 chrX: 71094692 - 71096928 0.1256 0.2592 0.1335 2.0629
ZRSR2 chrX: 15789350 - 15791219 0.0559 0.1021 0.0462 1.8252
RUNX1T1 chr8: 92102449 - 92105016 0.0558 0.1008 0.0450 1.8068
RHOH chr4: 40196452 - 40197679 0.1059 0.1914 0.0855 1.8067