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Table 4 DNA methylation around PE-related SNPs (GRCh37/hg19 assembly)

From: Epigenome-wide DNA methylation profiling of preeclamptic placenta according to severe features

Probe ID MAPINFO SNP_ID Control (n = 13) PE (n = 5) PE with severe feature (n = 8) P Bonferroni
Pa Pb Pc
cg11348599 29,073,223 rs192147271
rs74619608
rs550918608
0.59 0.51 0.53 0.030 0.037 0.358 1.000
cg15188434* 29,105,629 rs192139036 0.69 0.67 0.70 0.794 1.000 1.000 1.000
cg08962087 29,107,120 rs569310504
rs537887549
rs75417109
0.19 0.10 0.15 0.004 0.002 0.362 0.002
cg07027493# 29,138,219 rs7320190
rs560703568
0.47 0.48 0.47 0.975 1.000 1.000 1.000
cg10329331# 29,139,026 rs545690604
rs18598099
rs113006545
0.97 0.97 0.97 0.831 1.000 1.000 1.000
cg15887927 29,148,952 rs540334005
rs377281528
rs528914368
0.53 0.41 0.50 0.003 0.001 0.001 0.063
cg19371105 29,159,914 rs550630513
rs369261321
0.92 0.84 0.92 0.015 0.002 1.000 0.020
cg18469224 29,160,247 rs537961884 0.95 0.96 0.96 0.044 0.242 0.072 1.000
cg16463452 29,195,249 rs138779088 0.88 0.81 0.89 0.028 0.001 1.000 0.004
cg08931404 29,227,083 rs563719373
rs532541556
0.87 0.88 0.90 0.224 1.000 0.272 0.553
  1. Continuous variables are presented as mean
  2. Kruskal-Wallis test, followed by the Bonferroni correlation for multiple testing
  3. Pa control versus PE, Pb control versus PE with severe features, Pc PE versus PE with severe features
  4. PE-related SNPs: *rs149427560 (MAPINFO: 29,105,870); #rs4769613 (MAPINFO: 29,138,609); rs12050029 (MAPINFO: 29,227,519)