From: Epigenome-wide DNA methylation profiling of preeclamptic placenta according to severe features
Characteristics | Control (n = 13) | PE (n = 5) | PE with severe feature (n = 8) |
---|---|---|---|
Maternal age, years | 35.7 ± 4.2 | 37.4 ± 5.0 | 35.6 ± 2.1 |
Prepregnancy body mass index, kg/m2 | 24.1 ± 3.5 | 23.7 ± 4.3 | 24.8 ± 4.4 |
Gravidity (n) | 2.3 ± 0.9 | 1.8 ± 0.8 | 1.9 ± 0.6 |
Nulliparous, % | 46.2 (6/13) | 60 (3/5) | 87.5 (7/8) |
Blood pressure and proteinuria | |||
 SBP at bookinga, mm Hg | 111.4 ± 10.9 | 127.2 ± 10.9 | 123.9 ± 14.1 |
 DBP at bookinga, mm Hg | 64.9 ± 12.1 | 78.4 ± 4.2 | 74.8 ± 8.7 |
 Highest SBP, mm Hg | 122.5 ± 8.7 | 151.2 ± 7.2 | 155.0 ± 6.7 |
 Highest DBP, mm Hg | 72.2 ± 7.4 | 93.4 ± 6.6 | 97.3 ± 5.9 |
 Proteinuria (dipstick result) | 0 | 2.4 ± 0.9 | 1.9 ± 0.4 |
Pregnancy outcome | |||
 Gestational age at delivery, weeks | 38.8 ± 1.2 | 38.4 ± 1.9 | 35.8 ± 2.4 |
 Delivery < 37 weeks, % | 0 (0/13) | 0 (0/5) | 62.5 (5/8) |
 Birthweight, kg | 3.3 ± 0.3 | 3.1 ± 0.5 | 2.0 ± 0.5 |
 Fetal growth percentage | 46.7 ± 6.3 | 42.4 ± 7.4 | 5.4 ± 4.1 |
 Neonatal intensive care unit admission, % | 0 (0/13) | 40 (2/5) | 87.5 (7/8) |
 Male infant, % | 46.2 (6/13) | 20 (1/5) | 62.5 (5/8) |