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Table 1 Patient demographics and characteristics

From: Epigenome-wide DNA methylation profiling of preeclamptic placenta according to severe features

Characteristics Control (n = 13) PE (n = 5) PE with severe feature (n = 8)
Maternal age, years 35.7 ± 4.2 37.4 ± 5.0 35.6 ± 2.1
Prepregnancy body mass index, kg/m2 24.1 ± 3.5 23.7 ± 4.3 24.8 ± 4.4
Gravidity (n) 2.3 ± 0.9 1.8 ± 0.8 1.9 ± 0.6
Nulliparous, % 46.2 (6/13) 60 (3/5) 87.5 (7/8)
Blood pressure and proteinuria
 SBP at bookinga, mm Hg 111.4 ± 10.9 127.2 ± 10.9 123.9 ± 14.1
 DBP at bookinga, mm Hg 64.9 ± 12.1 78.4 ± 4.2 74.8 ± 8.7
 Highest SBP, mm Hg 122.5 ± 8.7 151.2 ± 7.2 155.0 ± 6.7
 Highest DBP, mm Hg 72.2 ± 7.4 93.4 ± 6.6 97.3 ± 5.9
 Proteinuria (dipstick result) 0 2.4 ± 0.9 1.9 ± 0.4
Pregnancy outcome
 Gestational age at delivery, weeks 38.8 ± 1.2 38.4 ± 1.9 35.8 ± 2.4
 Delivery < 37 weeks, % 0 (0/13) 0 (0/5) 62.5 (5/8)
 Birthweight, kg 3.3 ± 0.3 3.1 ± 0.5 2.0 ± 0.5
 Fetal growth percentage 46.7 ± 6.3 42.4 ± 7.4 5.4 ± 4.1
 Neonatal intensive care unit admission, % 0 (0/13) 40 (2/5) 87.5 (7/8)
 Male infant, % 46.2 (6/13) 20 (1/5) 62.5 (5/8)
  1. Continuous variables are presented as mean ± standard deviation, and discrete variables are percentages (n/N)
  2. aFirst blood pressure measured in pregnancy, all in the first trimester