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Table 3 Top 20 DMCs within the promoter region

From: Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy

Gene CpG location q value Methylation difference (%) Type Gene description
DOK7 chr4:3486002 2.17E−38 −50.10 Protein_coding Docking protein 7
MIR3648-1 chr21:9825780 1.02E−20 −30.84 MicroRNA MicroRNA 3648-1
GALNT9 chr12:132692165 2.53E−33 28.53 Protein_coding Polypeptide N-acetylgalactosaminyltransferase 9
C15orf57 chr15:40858818 5.12E−24 28.46 Protein_coding Chromosome 15 open reading frame 57
TNNT3 chr11:1939527 5.15E−08 −28.28 Protein_coding Troponin T type 3 (skeletal, fast)
P2RX1 chr17:3821014 4.19E−34 −27.10 Protein_coding Purinergic receptor P2X, ligand-gated ion channel, 1
LMF1 chr16:1022800 2.21E−11 −26.96 Protein_coding Lipase maturation factor 1
VAC14-AS1 chr16:70787597 7.18E−07 −26.42 Antisense VAC14 antisense RNA 1
HOXA-AS3 chr7:27179251 4.33E−06 −25.87 Antisense HOXA cluster antisense RNA 3
LOC100129931 chr4:7048841 1.02E−58 25.30 ncRNA Uncharacterized LOC100129931
LINC01168 chr10:134778467 1.01E−13 −25.27 LincRNA Long intergenic non-protein coding RNA 1168
SNORD59B chr12:57038157 1.58E−05 24.49 snoRNA Small nucleolar RNA, C/D box 59B
SNAI3 chr16:88753392 5.22E−06 −24.27 Protein_coding Snail homolog 3 (Drosophila)
MIR3648-1 chr21:9825613 1.59E−33 24.04 MicroRNA MicroRNA 3648-1
MIR3687-1 chr21:9826027 2.08E−17 −24.02 MicroRNA MicroRNA 3687-1
LOC100134317 chr19:36800758 5.25E−20 23.97 ncRNA Uncharacterized LOC100134317
MIR663AHG chr20:26189971 1.66E−07 23.77 MicroRNA MIR663A host gene
AEBP2 chr12:19592255 2.69E−07 23.69 Protein_coding AE binding protein 2
CABLES1 chr18:20712894 1.01E−05 23.43 Protein_coding Cdk5 and Abl enzyme substrate 1
GBP5 chr1:89739007 1.41E−35 22.80 Protein_coding Guanylate binding protein 5