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Table 2 The 15 most upregulated and downregulated DEGs

From: Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy

Gene symbol

Entrez ID

Annotation

Log2FoldChange

Adjusted p value

RPS29

6189

Ribosomal protein S3A

1.51

1.50E−06

ANKRD36B

57730

Ankyrin repeat domain 36B

1.30

1.64E−07

ANKRD36

375248

Ankyrin repeat domain 36

1.29

7.32E−11

SPTBN5

51332

Spectrin beta, non-erythrocytic 5

1.29

6.03E−06

SLC7A5P2

27173

Solute carrier family 39 member 1

1.21

1.84E−07

HERC2P2

400322

Hect domain and RLD 2 pseudogene 2

1.18

1.67E−07

MIR143HG

728264

Cardiac mesoderm enhancer-associated noncoding RNA

1.18

2.62E−06

KAT2A

2648

Lysine acetyltransferase 2A

1.17

5.24E−08

CCNL2

81669

Cyclin L2

1.15

4.74E−13

MYO15B

55930

Myosin VC

1.14

3.50E−09

LOC440300

440300

Chondroitin sulfate proteoglycan 4 pseudogene

1.14

5.28E−08

LINC00342

378805

Long intergenic non-protein coding RNA, p53-induced transcript

1.13

4.40E−08

LENG8

114823

Leukocyte receptor cluster member 8

1.12

1.92E−10

SMG1P3

100271836

SMG1P3, nonsense mediated mRNA decay associated PI3K related kinase pseudogene 3

1.12

2.94E−08

NEAT1

283131

Nuclear paraspeckle assembly transcript 1 (non-protein coding)

1.11

1.52E−11

ASPN

54829

Asporin

−1.11

1.68E−06

PI16

221476

Peptidase inhibitor 16

−1.12

3.13E−06

SELPLG

6404

Selectin P ligand

−1.14

3.32E−04

WISP2

8839

WNT1 inducible signaling pathway protein 2

−1.16

4.30E−07

MRC1

4360

Mannose receptor C-type 1

−1.19

2.10E− 05

SELL

6402

Selectin L

−1.19

3.22E−04

CYBB

1536

Cytochrome b-245 beta chain

−1.22

1.74E−05

CCDC80

81576

Coiled-coil domain containing 130

−1.23

1.93E−12

C1QA

712

Complement C1q A chain

−1.23

1.24E−04

LYVE1

10894

Lymphatic vessel endothelial hyaluronan receptor 1

−1.28

2.11E−06

MPEG1

219972

Macrophage expressed 1

−1.31

2.06E−07

CD14

920

CD4 molecule

−1.36

4.02E−07

F13A1

2162

Coagulation factor XIII A chain

−1.40

1.00E−08

C1QC

714

Complement C1q C chain

−1.45

1.45E−08

C1QB

713

Complement C1q B chain

−1.50

6.92E−08