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Table 1 Clinical characteristics and neuropathy measures of groups 1 and 2

From: Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy

Group

Group 1 (n = 21)

Group 2 (n = 32)

p value

Age

57.4 ± 9.1

55.7 ± 7.6

0.46

Sex (male/female)

13/8

20 /12

0.77

Body mass index (kg/m2)

30.1 ± 6.0

31 ± 5.6

0.55

HbA1c (%)

8.7 ± 1.6

7.8 ± 1.4

0.04*

Cholesterol (mmol/L)

5.7 ± 1.4

5.9 ± 1.1

0.56

Triglyceride (mmol/L)

2.8 ± 1.8

2.8 ± 2.5

0.96

Diabetes duration (years)

8.6 ± 6.9

9.9 ± 6.2

0.50

MFD, baseline (fibers/mm2)

3783.2 ± 1714.9

3073.7 ± 1567.3

0.14

MFD, 52 weeks (fibers/mm2)

3771.1 ± 1965.9

2942.4 ± 1750.2

0.13

MFD, change (fibers/mm2)

−12.1 ± 1062.2

−131.3 ± 1082.1

0.69

ALCAR treated, n (%)

15 (71.4%)

20 (62.5%)

0.56

  1. Values are the mean ± standard deviation (SD). p value was calculated by Student’s t test and Fisher’s exact test
  2. ALCAR acetyl-L-carnitine, MFD myelinated fiber density
  3. *p value < 0.05