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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy

Fig. 7

qPCR validation of genes with a similar direction of change in DNA methylation and gene expression. RNA was extracted from human sural nerve biopsies from group 1 (n  =  9–10) and group 2 (n  =  10), which was used as the relative control group (set to 100%), and quantified by RT-qPCR. Data were normalized to tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ) and expressed as % change calculated by the 2−ΔΔCT method. *p < 0.05 relative to group 2

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