Table 5 Multiple linear regression analysis showing the association of smoking and living in PM2.5 areas with AHRR (cg05575921) methylation in the study participants stratified by sex
From: AHRR cg05575921 methylation in relation to smoking and PM2.5 exposure among Taiwanese men and women
Variable | Men | Women | ||
|---|---|---|---|---|
β | P value | β | P value | |
Smoking status (reference: never) | ||||
 Former | − 0.01996 | 0.0374 | − 0.04276 | < 0.0001 |
 Current | − 0.17221 | < 0.0001 | − 0.17706 | < 0.0001 |
 P-trend | < 0.0001 | < 0.0001 | ||
Area (reference: north) | ||||
 North-center | − 0.00577 | 0.3174 | 0.00092 | 0.9198 |
 Center | − 0.00935 | 0.0820 | − 0.01770 | 0.0361 |
 South | − 0.01620 | 0.0016 | − 0.02076 | 0.0092 |
 P-trend | 0.0013 | 0.0025 | ||
Exercise (no) | ||||
 Yes | 0.00294 | 0.4651 | 0.00001 | 0.9986 |
Age | − 0.00033 | 0.0939 | − 0.00045 | 0.1278 |
BMI | 0.00105 | 0.0407 | − 0.00006 | 0.9477 |
Alcohol drinking (reference: no) | ||||
 Former | 0.03356 | 0.0977 | − 0.00934 | 0.4539 |
 Current | 0.03177 | 0.1127 | 0.00115 | 0.9022 |
Secondhand smoke exposure (reference: no) | ||||
 Yes | 0.00361 | 0.5589 | − 0.00060 | 0.9489 |