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Table 2 Multiple linear regression analysis showing the association of smoking and PM2.5 with AHRR cg05575921 methylation in the study participants

From: AHRR cg05575921 methylation in relation to smoking and PM2.5 exposure among Taiwanese men and women

Variable Model 1 Model 2
β P value β P value
Smoking status (reference: never)
 Former − 0.03909 < 0.0001 − 0.02221 < 0.0001
 Current − 0.17536 < 0.0001 − 0.11578 < 0.0001
 P-trend < 0.0001 < 0.0001
PM2.5 − 0.00141 < 0.0001 − 0.00070 0.0120
Sex (reference: women)
 Men − 0.01870 < 0.0001 − 0.01843 < 0.0001
Age − 0.00044 0.0145 − 0.00018 0.2636
Exercise (reference: no)
 Yes 0.00077 0.8404 0.00052 0.8772
BMI 0.00060 0.2344 0.00014 0.7488
Alcohol drinking (reference: no)
 Former − 0.00512 0.5931 − 0.00821 0.3264
 Current 0.00157 0.8318 0.00539 0.4041
Secondhand smoke (reference: no)
 Yes 0.00136 0.8100 − 0.00204 0.6793
F2LR3 cg03636183 methylation 0.71185 < 0.0001
  1. Model 1: not adjusted for F2LR3 cg03636183 methylation. Model 2: adjusted for F2LR3 cg03636183 methylation