Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes

Table 1 Average classification accuracy based on 100 repetitions of 5-fold cross validation of four tissue-type classifications when using only unmethylated INS, only unmethylated CHTOP-817, or both unmethylated INS + CHTOP-817 together with a P < 10⁻³⁰

	INS	CHTOP-817	INS + CHTOP-817
β cells vs. other tissues	80.6	86	88.8
Islet cells vs. other tissues	98.3	76.8	100
Pancreatic cells vs. other tissues	70.8	92.7	94.8
β cells vs. α cells vs. other tissues	86	68.7	92.7

ISSN: 1868-7083