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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes

Fig. 5

Circulating differentially methylated CHTOP-817 and INS DNA levels in control, new-onset T1D, and autoantibody-negative first-degree relatives (FDRs) of individuals with T1D. DNA was isolated from serum, bisulfite-converted, and differentially methylated CHTOP-817 and INS levels were analyzed by droplet dPCR. a Log of unmethylated CHTOP-817 DNA levels; b log of methylated CHTOP-817 DNA levels; c log of unmethylated INS DNA levels; d log of methylated INS DNA levels. Data are presented as mean ± SEM and each symbol represents an individual donor. *P < 0.05 for the comparisons indicated

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Clinical Epigenetics

ISSN: 1868-7083

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