Table 1 Cohort characteristics
| Â | n | Mean | Median | Range | SD |
|---|---|---|---|---|---|
LBC1936 wave 1 | 1091 | – | – | – | – |
 Age (years) | – | 69.53 | 69.54 | 67.61, 71.29 | 0.83 |
 Sex (% female) | 49.8 | – | – | – | – |
 CRP (mg/L) | 1054 | 5.26 | 3.0 | 1.5, 90 | 6.78 |
 DNAm CRP | 894 | − 0.019 | − 0.019 | − 0.024, − 0.015 | 0.0013 |
 Genetic score | 1005 | 2.16 | 2.16 | 1.23, 2.83 | 0.25 |
gf | 1070 | 0.096 | 0.12 | − 3.43, 3.017 | 1.0091 |
 BMI (kg/m2) | 1083 | 27.78 | 27.39 | 16.023, 48.52 | 4.36 |
 Alcohol (units/week) | 1063 | 9.93 | 6 | 0, 70 | 12.12 |
 Smoking status | 894 | − | − | − | − |
  Current | 102 | − | − | − | − |
  Ex | 375 | − | − | − | − |
  Never | 417 | − | − | − | − |
 SIMD | 1083 | 5342 | 5342 | 4, 6505 | 1907 |
Generation Scotland | 7028 | – |  |  | – |
 Age (years) | – | 50.89 | 52.75 | 18, 93.3 | 12.96 |
 Sex (% female) | 58.2 | – | – | – | – |
 CRP (ng/mL) | 419 | 2.65 | 1.21 | 0.15, 63.25 | 5.59 |
 DNAm CRP | 7028 | − 0.012 | − 0.013 | − 0.016, − 0.0089 | < 0.001 |
 Genetic score | 7028 | 2.15 | 2.17 | 1.14, 2.91 | 0.26 |
gf | 6880 | 0.0063 | 0.042 | − 4.15, 3.89 | 0.99 |
 BMI (kg/m2) | 6988 | 26.93 | 26.15 | 14.78, 51.29 | 5.089 |
 Alcohol (units/week) | 6414 | 10.49 | 8 | 0, 73 | 11.017 |
 Smoking status | 6854 | – | – | – | – |
  Current | 1135 | – | – | – | – |
  Ex | 2167 | – | – | – | – |
  Never | 3552 | – | – | – | – |
SIMD | 6693 | 3953 | 4456 | 3, 6505 | 1857 |