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Table 1 Cohort characteristics

From: Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

  n Mean Median Range SD
LBC1936 wave 1 1091
 Age (years) 69.53 69.54 67.61, 71.29 0.83
 Sex (% female) 49.8
 CRP (mg/L) 1054 5.26 3.0 1.5, 90 6.78
 DNAm CRP 894 − 0.019 − 0.019 − 0.024, − 0.015 0.0013
 Genetic score 1005 2.16 2.16 1.23, 2.83 0.25
gf 1070 0.096 0.12 − 3.43, 3.017 1.0091
 BMI (kg/m2) 1083 27.78 27.39 16.023, 48.52 4.36
 Alcohol (units/week) 1063 9.93 6 0, 70 12.12
 Smoking status 894
  Current 102
  Ex 375
  Never 417
 SIMD 1083 5342 5342 4, 6505 1907
Generation Scotland 7028   
 Age (years) 50.89 52.75 18, 93.3 12.96
 Sex (% female) 58.2
 CRP (ng/mL) 419 2.65 1.21 0.15, 63.25 5.59
 DNAm CRP 7028 − 0.012 − 0.013 − 0.016, − 0.0089 < 0.001
 Genetic score 7028 2.15 2.17 1.14, 2.91 0.26
gf 6880 0.0063 0.042 − 4.15, 3.89 0.99
 BMI (kg/m2) 6988 26.93 26.15 14.78, 51.29 5.089
 Alcohol (units/week) 6414 10.49 8 0, 73 11.017
 Smoking status 6854
  Current 1135
  Ex 2167
  Never 3552
SIMD 6693 3953 4456 3, 6505 1857
  1. LBC1936 Lothian Birth Cohort 1936, CRP C-reactive protein, DNAm DNA methylation, gf general cognitive ability score, SIMD Scottish Index of Multiple Deprivation, BMI body mass index